One night in spring 2008, the Blind Boys of Alabama played a sold-out show at the iconic New Orleans's club Tipitina's, with special guests.

A music documentary about the changing face of the music business. Lorde, Melissa Etheridge, Questlove, Sharon Jones, Steve Aoki, Susan Tedeschi, and Derek Trucks perform and discuss their personal history, emergence as stars, and perceptions of the business side of things. Additional artists and heritage artists are also featured, including Bruno Mars, Ed Sheeran, Madonna, and the Ramones.