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Marvel's top merc is back is business and better than ever! We all know Wade Wilson is one of the leading guns-for-hire in the Marvel Universe (even if he is simultaneously the most annoying one), but now he's pushing to make that recognition official. Deadpool is auditioning for the elite group of assassins known as the Atelier, and he has 48 hours to kill one of the world's most famous super villains: Doctor Octopus! Only problem? He's been kidnapped,...

"What if everything you thought was funny about Deadpool was actually just disturbing? What if he decided to kill everyone and everything that makes up the Marvel Universe? What if he actually pulled it off? Would that be FUN for you? The Merc with a Mouth takes a turn for the twisted in a horror comic like no other!"--P. [4] of cover.

When dead U.S. presidents start rising from the grave to terrorize the country, the world's high-profile superheroes can't afford to risk their public image by defeating them, so they ask Deadpool--who already has a sullied reputation--to do the deed.

"Landau, Luckman, and Lake want Deadpool to rebuild himself as a hero but he'll be lucky to pull himself together as he is! His healing factor's down, and the only thing that'll juice it up is a dose of the Incredible Hulk's blood administered by the Weapon X alumnus who helped make Deadpool what he is in the first place! Not even mad science can mend a torn heart, though, as Deadpool's infatuation with X-Force's Siryn (later of X-FACTOR) is challenged...

Joe Kelly's riotous, character-defining run continues! Deadpool battles the revamped Great Lakes Avengers - but can he and Blind Al escape the past when they're hurled into the pages of a Silver Age Spider-Man story?! Then, as T-Ray and Typhoid Mary continue to torment Deadpool, will X-Force's Siryn help save him from his own self-destructive tendencies? As Wade inches closer to the edge, the man called Ajax is cleaning house, and he wants Deadpool's...

"When Deadpool goes Hollywood, he's sure to bring his wall-crawling bud along for the ride--after all, Spidey is no stranger to selling out! In the proud DP tradition, a "lost" issue of Amazing Spider-Man flashes us back to one of our pun-happy pair's earliest meetings! Then, Spidey and Deadpool meet Penn and Teller, for reals, in a tale penned by Penn himself! When both our heroes are alone for the holidays, that means they're the only ones who can...

zDeadpool finds his voice in a character-defining and hilarious run! The mysterious corporation Landau, Luckman & Lake believes Deadpool is their Chosen One--but does the Merc with a Mouth have it in him to be a hero? Wade's old pal Weasel and housemate-slash-prisoner Blind Al have their doubts., and fellow merc T-Ray is out to see Wade fail at all costs? Maybe the unstable Typhoid Mary can help him refocus? Naaah! Plus: When Deadpool's healing factor...